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GTP Importin Cargo GG DT PP NLS G D P G T P GEF GDP GTP G T P G T P Nucleoplasm Cytoplasm Cargo complex G D P NPC Pi H2O GAP EXPERIMENTAL FIGURE 12-20 The failure of nuclear transport to occur in permeabilized cultured cells in the absence of lysate demonstrates the involvement of soluble cytosolic components in the process. 4: Coherence of local orientation of a piece of cloth with regions of horizontal stripes (Fig. Urokinase is a relatively stable molecule.
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